Raquel Hontecillas Selected Research

Peroxisome Proliferator-Activated Receptors (PPAR)

1/2013	The role of peroxisome proliferator-activated receptor γ in immune responses to enteroaggregative Escherichia coli infection.
10/2012	Expression of PPAR γ in intestinal epithelial cells is dispensable for the prevention of colitis by dietary abscisic acid.
1/2012	Probiotic bacteria produce conjugated linoleic acid locally in the gut that targets macrophage PPAR γ to suppress colitis.
1/2012	Modeling the role of peroxisome proliferator-activated receptor γ and microRNA-146 in mucosal immune responses to Clostridium difficile.
12/2011	Suppression of intestinal inflammation and inflammation-driven colon cancer in mice by dietary sphingomyelin: importance of peroxisome proliferator-activated receptor γ expression.
1/2011	Abscisic acid regulates inflammation via ligand-binding domain-independent activation of peroxisome proliferator-activated receptor gamma.
1/2011	Treatment of Obesity-Related Complications with Novel Classes of Naturally Occurring PPAR Agonists.
1/2011	Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ.
10/2010	Abscisic acid synergizes with rosiglitazone to improve glucose tolerance and down-modulate macrophage accumulation in adipose tissue: possible action of the cAMP/PKA/PPAR γ axis.
4/2010	Immunoregulatory actions of epithelial cell PPAR gamma at the colonic mucosa of mice with experimental inflammatory bowel disease.

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Raquel Hontecillas Research Topics

Disease

31	Inflammation (Inflammations) 01/2022 - 07/2002
19	Colitis 01/2023 - 07/2002
18	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 09/2004
14	Obesity 01/2020 - 12/2006
9	Infections 12/2017 - 01/2010
7	Insulin Resistance 01/2020 - 02/2007
6	Crohn Disease (Crohn's Disease) 11/2023 - 10/2012
6	Clostridium Infections 07/2023 - 08/2014
5	Ulcerative Colitis 11/2023 - 03/2019
4	Autoimmune Diseases (Autoimmune Disease) 11/2023 - 07/2002
4	Virus Diseases (Viral Diseases) 10/2021 - 10/2003
4	Neoplasms (Cancer) 01/2017 - 07/2002
3	Diarrhea 01/2023 - 01/2014
3	Body Weight (Weight, Body) 01/2020 - 06/2010
3	Weight Loss (Weight Reduction) 01/2014 - 04/2010
3	Malnutrition (Nutritional Deficiencies) 01/2014 - 01/2013
3	Weight Gain 01/2012 - 10/2010
2	Type 2 Diabetes Mellitus (MODY) 07/2019 - 03/2011
2	Communicable Diseases (Infectious Diseases) 06/2014 - 01/2012
2	Colonic Neoplasms (Colon Cancer) 12/2011 - 01/2009
2	Atherosclerosis 12/2010 - 07/2002
2	Colorectal Neoplasms (Colorectal Cancer) 09/2010 - 03/2010
2	Hypertrophy 01/2008 - 02/2007
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2008 - 12/2006
1	Opportunistic Infections (Opportunistic Infection) 07/2023
1	Pseudomembranous Enterocolitis (Pseudomembranous Colitis) 01/2023
1	Asymptomatic Infections 01/2023
1	Hemorrhage 01/2022
1	Hyperplasia 10/2021
1	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2021
1	Invasive Pulmonary Aspergillosis 01/2020
1	Prediabetic State (Prediabetes) 07/2019
1	Papillomavirus Infections 01/2017
1	Reinfection 01/2017
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2015
1	Breast Neoplasms (Breast Cancer) 08/2014
1	Gastritis 07/2014
1	Persistent Infection 07/2014

Drug/Important Bio-Agent (IBA)

16	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2013 - 06/2006
16	PPAR gammaIBA 01/2012 - 07/2002
13	Abscisic AcidIBA 01/2020 - 02/2007
11	Ligases (Synthetase)IBA 11/2023 - 03/2011
11	lanthionineIBA 11/2023 - 03/2011
10	Conjugated Linoleic AcidsIBA 08/2016 - 07/2002
8	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 02/2007
7	Insulin (Novolin)FDA Link 01/2020 - 04/2008
7	Dextrans (Dextran)FDA Link 01/2018 - 06/2006
6	CytokinesIBA 12/2019 - 07/2002
6	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2017 - 06/2006
5	Anti-Bacterial Agents (Antibiotics)IBA 07/2023 - 01/2015
5	punicic acidIBA 06/2013 - 04/2009
4	Proteins (Proteins, Gene)FDA Link 08/2014 - 03/2011
4	Plant Growth Regulators (Plant Hormones)IBA 06/2013 - 04/2008
3	LigandsIBA 06/2014 - 12/2006
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 06/2010 - 01/2010
2	NX-13IBA 01/2022 - 12/2019
2	Antigen-Antibody Complex (Immune Complex)IBA 10/2021 - 01/2015
2	Blood Glucose (Blood Sugar)IBA 01/2020 - 01/2012
2	Interleukin-10 (Interleukin 10)IBA 01/2017 - 07/2002
2	Antiviral Agents (Antivirals)IBA 01/2017 - 10/2003
2	Pattern Recognition ReceptorsIBA 01/2015 - 12/2014
2	nitazoxanide (NTZ)FDA Link 08/2014 - 06/2013
2	Interferon-gamma (Interferon, gamma)IBA 07/2014 - 07/2002
2	Virulence Factors (Pathogenicity Factors)IBA 07/2014 - 06/2013
2	Interleukin-17 (Interleukin 17)IBA 07/2014 - 01/2013
2	Dietary Fiber FDA Link 06/2013 - 07/2011
2	eleostearic acidIBA 06/2013 - 01/2011
2	AntigensIBA 01/2013 - 01/2007
2	AzoxymethaneIBA 12/2011 - 03/2010
2	Rosiglitazone (Avandia)FDA Link 01/2011 - 10/2010
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 09/2010 - 06/2006
2	Messenger RNA (mRNA)IBA 02/2007 - 10/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2007 - 06/2006
2	Vitamin D FDA LinkGeneric 01/2007 - 07/2002
1	Deoxyglucose (2 Deoxy D glucose)IBA 01/2023
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2022
1	VaccinesIBA 10/2021
1	Imiquimod (Aldara)FDA LinkGeneric 10/2021
1	micaIBA 01/2021
1	Investigational DrugsIBA 01/2020
1	Dextran SulfateIBA 12/2019
1	IonomycinIBA 12/2019
1	Interleukin-8 (Interleukin 8)IBA 12/2019
1	Interleukin-6 (Interleukin 6)IBA 12/2019
1	DiazooxonorleucineIBA 01/2018
1	SodiumIBA 01/2018
1	Glutamine (L-Glutamine)FDA Link 01/2018
1	RNA (Ribonucleic Acid)IBA 12/2017
1	AntibodiesIBA 01/2017
1	NucleotidesIBA 01/2017
1	N,N- bis(benzimidazolylpicolinoyl)piperazineIBA 11/2016
1	AS 8IBA 01/2016
1	amixicileIBA 08/2014
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 08/2014
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 08/2014
1	interleukin-21 (interleukin 21)IBA 07/2014
1	ChemokinesIBA 07/2014

Therapy/Procedure

11	Therapeutics 11/2023 - 08/2010
1	Glycemic Control 01/2020
1	Fecal Microbiota Transplantation 01/2017